Pain After Surgery
Tuesday, September 5, 2017
Location: Bella Center | Hall I
IASP and EFIC have declared 2017 the Global Year Against Surgical Pain.
The Special Interest Group 'Acute Pain' of the IASP has therefore organized a Satellite Meeting at the 10th Congress of the European Pain Federation (EFIC) in Copenhagen, Denmark on 5 September 2017. The meeting offers a line-up of invited world-renowned speakers in the area of postoperative pain management. The program will address the latest progress in postoperative pain management and a vision of things to come. Other important topics will be the progression of acute postoperative to chronic post-surgical pain, risk factors for such a progression and possibilities for its prevention and treatment.
Please click here for the Symposium Programme.
Cost: 80 Euro
To register for this Satellite Meeting, please click here.
Neural Circuits of Pain
September 3-5, 2017
Heidelberg and Schwetzingen, Germany
Studying molecular mechanisms of chronic pain has been an important focus of pain research. However, the nature and plasticity of neural circuits that mediate the sensory and emotional components of pain are still enigmatic. This conference will focus on interrogating, discussing and debating structural and functional understanding of circuits and networks underlying sensory and affective components of pain and their modulation by circumstances which induce structural reorganization and functional plasticity, including disease states, negative emotions and stress. Therefore, this meeting will bring together internationally leading thinkers and experts with next generation puzzle-solvers to discuss latest insights and advances on neural circuits at all levels in pain pathways and will cover novel data in basic science as well as clinical research. The venues of the symposium are centrally situated in historic parts of the cities of Heidelberg and Schwetzingen and are easily accessible via public transportation. There is sufficient time after the satellite symposium to travel to the EFIC meeting, Copenhagen, Denmark. The number of attendees will be limited to approximately 150-180 to facilitate scientific exchange.
We are looking forward to welcoming you in Heidelberg!
Rohini Kuner, Pharmacology Institute, Heidelberg University, Germany.
Herta Flor, Central Institute of Mental Health, Mannheim, Germany.
Basbaum, Xu Zhang, Thomas Sears, Hermann Handwerker, Wilfried Jänig,
Didier Bouhassira, Martyn Goulding, Sigrid Elsenbruch, Gary Lewin, Tor
Wager, Vania Apkarian, Frank Porreca, Eija Kalso, Carla Nau, Frank
Keefe, Andrew Rice, Mark H. Tuszynski, Qiufu Ma, Ceng Luo, Moqrich Aziz ,
Yves De Koninck.
Dr. Pooja Gupta and Sabine Hoffmann
On September 3, 2017
Heidelberg Marriott Hotel
On September 4 & 5, 2017
Official website: www.paincircuits.de
Registration and fees:
Registration is mandatory for all the attendees. Please check the website for more details.
Faculty and industry scientists: 350 euros
Postdoctoral scientists: 300 euros
Heidelberg/Mannheim faculty and postdoctoral scientists: 300 euros
Students: 250 euros
Registration fees include coffee breaks, non-alcoholic beverages during the sessions, lunch and dinner on all the days and the registration materials.
Please provide the proof of your status (graduate student, medical
student or junior postdoctoral fellow) via student identity card or the
letter of support from your supervisor.
Enquiries: Dr. Pooja Gupta
Chronic Post-Surgical Pain
Monday, September 04, 2017
13:00–17:30 with Reception to follow
Location: Bella Center | Room 19
IASP and EFIC have declared 2017 the Global Year Against Surgical Pain
In recognition of the incidence, severity and negative consequences of chronic post-surgical pain (CPSP), the topic of preventing CPSP will be discussed in a moderated panel setting. The panel will also discuss novel approaches to preventing CPSP illustrated by the development path of AYX1, a transcription factor decoy currently in mid-stage clinical trials.
Despite recent advancements in surgical techniques and post-surgical care, the management of pain following surgery remains a significant challenge. Current treatment options often fail to provide adequate pain relief and leave patients burdened with undesirable side effects. From a pharmacological perspective, by blocking only one or a few effectors (receptor, ion channel, etc.) for a limited period of time, these treatment options provide partial and temporary relief within a complex and degenerate system. For example, nerve conduction blockade can temporarily address acute post-surgical pain, but it is typically effective only when the local anesthetic is present and has not been shown to consistently influence the incidence of CPSP.
Given the pharmacological profile of current treatment options, the focus has been on acute post-surgical pain on one end and chronic post-surgical pain on the other. Little attention has been directed to the weeks in between, which are critical for rehabilitation and often reflect the transition to CPSP. The types of pain (pain at rest and with movement), the course of pain resolution (or lack of resolution), and the impact on health economics during that period will be discussed.
The development of new agents capable of accelerating the resolution of pain during the weeks following surgery and preventing CPSP would be a valuable addition to the current pharmacopeia. Potential targets for such pain-modifying agents include molecular triggers responsible for establishing and maintaining long-term pain, such as Early Growth Response 1 (EGR1). AYX1 is a development-stage transcription factor decoy that inhibits EGR1 with a single intrathecal injection at the time of surgery. The development of compounds like AYX1 will serve as a guide to discussing novel approaches to alter the continuum of pain and prevent CPSP.
Please join us for a moderated expert panel discussion of these issues to help advance the understanding of definition and preventive treatment of chronic postsurgical pain. Be sure to bring your questions and concerns regarding these issues, as well.
Registration includes refreshments during breaks and an evening reception.
Cost: 40 Euro
Please click here to Register Now!